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The Aetiology Of Depression (Mdd And Sub Clinical Forms) In Diabetes Is Still Poorly Understood, With Bio-Medical And Psychosocial Factors Likely To Interact [Karlson,Agardh, 1997; Talbot, Nouwen, 2000]. Depression Has Been Found To Be Associated With Poorer Self-Care And Metabolic Control [Lustman Et Al, 2000; Ciechanowski Et Al., 2000] And A Three-Fold Increased Risk Of Diabetes-Related Complications, Including Heart Disease And Stroke[De Groot Et Al., 2001]. Interestingly, Mdd Has Also Been Shown To Independently Predict Incidence Of Coronary Artery Disease [Carney Et Al., 1994] And Onset Of Type 2 Diabetes [Eaton Et Al., 1996; Kawamaki Et Al., 1999].However, To Date, The Underlying Mechanisms, Whether Behavioural, Biological, Or Genetic Are Unknown.

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