Born in Knoxville, Tennessee, on July 25, 1982, he was discovered at age 10 by director Joel Schumacher and was cast in the motion picture The Client (1994), which starred Susan Sarandon and Tommy Lee Jones. Although this would be his zenith, he went on to appear in other films, including The Cure (1995), Tom and Huck (1995), Sleepers (1996), and Apt Pupil (1998). Renfro won The Hollywood Reporter's Young Star Award in 1995 and was nominated as one of People magazine's "Top 30 Under 30," though addiction problems in his teens and early 20s led to several police arrests and hampered his career. He died of a drug overdose in January 2008, aged 25